|
Mutation Information
|
Mutation Site
|
I62V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Country
|
Brazilian;African |
Literature Information
|
PubMed PMID
|
32863004
|
|
Published Year
|
2020 |
|
Journal
|
Biochemical and biophysical research communications |
|
Title
|
Conformational landscape of non-B variants of HIV-1 protease: A pulsed EPR study. |
|
Author
|
Tran TT,Liu Z,Fanucci GE |
|
Evidence
|
Findings show that Subtypes F and H HIV-1 PR adopt a primarily closed conformation in the unbound state with two secondary mutations, D60E and I62V, postulated to be responsible for the increased probability for closed conformation.
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HIV Mutation Detail Information