Mutation Information
Mutation Site
|
I573L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Env |
Literature Information
PubMed PMID
|
32098152
|
Published Year
|
2020 |
Journal
|
Viruses |
Title
|
Identification of HIV-1 Envelope Mutations that Enhance Entry Using Macaque CD4 and CCR5. |
Author
|
Roop JI,Cassidy NA,Dingens AS,Bloom JD,Overbaugh J |
Evidence
|
For example, CHR mutations Q653L and Q652F improved infection of 293Trhm cells 9- and 7-fold, respectively, whereas the most advantageous NHR mutation, I573L, improved infection 4-fold (Figure 3a).
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