HIV Mutation Detail Information

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Mutation Information

Mutation Site	I559P
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp41

Literature Information

PubMed PMID	24884783
Published Year	2014
Journal	Retrovirology
Title	Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits.
Author	Yasmeen A,Ringe R,Derking R,Cupo A,Julien JP,Burton DR,Ward AB,Wilson IA,Sanders RW,Moore JP,Klasse PJ
Evidence	We also explored the antigenic consequences of three different features of SOSIP.664 gp140 trimers: the engineered inter-subunit disulfide bond, the trimer-stabilizing I559P change in gp41ECTO, and proteolytic cleavage at the gp120-gp41ECTO junction

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation