|
Mutation Information
|
Mutation Site
|
I54V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
PIs |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
31878069
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Microorganisms |
|
Title
|
Prevalence of Non-B HIV-1 Subtypes in North Italy and Analysis of Transmission Clusters Based on Sequence Data Analysis. |
|
Author
|
Lorenzin G,Gargiulo F,Caruso A,Caccuri F,Focà E,Celotti A,Quiros-Roldan E,Izzo I,Castelli F,De Francesco MA |
|
Evidence
|
The most frequent non-nucleoside reverse-transcriptase inhibitor (NNRTI) mutations were K103N (16.6%) and K101Q/R (10%). The most frequent protease inhibitor (PI) mutations were V82I (66.6%), M46L (10%), and I54V (6.6%).
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HIV Mutation Detail Information