Mutation Information
Mutation Site
|
I54V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
31172041
|
Published Year
|
2019 |
Journal
|
ACS omega |
Title
|
Highly Drug-Resistant HIV-1 Protease Mutant PRS17 Shows Enhanced Binding to Substrate Analogues. |
Author
|
Agniswamy J,Kneller DW,Brothers R,Wang YF,Harrison RW,Weber IT |
Evidence
|
The three mutations M46L, G48V, and I54V in PRS17 flaps act to curl the tip of flaps (Figure 2A).
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