|
Mutation Information
|
Mutation Site
|
I54V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Relevant Drug
|
amprenavir (APV) |
|
Country
|
Taiwan(China) |
Literature Information
|
PubMed PMID
|
28107423
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2017 |
|
Journal
|
PloS one |
|
Title
|
Characterization of the Drug Resistance Profiles of Patients Infected with CRF07_BC Using Phenotypic Assay and Ultra-Deep Pyrosequencing. |
|
Author
|
Huang SW,Li WY,Wang WH,Lin YT,Chou CH,Chen M,Huang HD,Chen YH,Lu PL,Wang SF,Oka S,Chen YA |
|
Evidence
|
For APV, the low-frequency PI DR variants harboring the major mutation I54V had positive correlation with phenotypic PI DR (R = 0.91, p< 0.01).
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HIV Mutation Detail Information