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HIV Mutation Detail Information

> I54V Search Result


Mutation Information
Mutation Site I54V
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Relevant Drug darunavir (DRV)
Literature Information
PubMed PMID 27992544
Published Year 2016
Journal PloS one
Title Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics.
Author Agniswamy J,Louis JM,Roche J,Harrison RW,Weber IT
Evidence The flaps of PRS17 harbor 3 mutations, M46L, G48V and I54V.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation