HIV Mutation Detail Information

> I54V Search Result


Mutation Information
Mutation Site I54V
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Relevant Drug lopinavir(LPV);ritonavir
Country UK
Literature Information
PubMed PMID 22110581
Disease HIV infection/AIDS
Published Year 2011
Journal PloS one
Title Can linear regression modeling help clinicians in the interpretation of genotypic resistance data? An application to derive a lopinavir-score.
Author Cozzi-Lepri A,Prosperi MC,Kjær J,Dunn D,Paredes R,Sabin CA,Lundgren JD,Phillips AN,Pillay D,EuroSIDA Study.,United Kingdom CHIC/United Kingdom HDRD Study.
Evidence Our analysis identified mutations V82A, I54V, K20I and I62V, which were associated with reduced viral response and mutations I15V and V91S which determined lopinavir/r hypersensitivity.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation