HIV Mutation Detail Information

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Mutation Information

Mutation Site	I54L
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	PIs
Country	France

Literature Information

PubMed PMID	33409332
Disease	HIV infection/AIDS
Published Year	2020
Journal	Open forum infectious diseases
Title	A Low Level of Darunavir Resistance-Associated Mutation Emergence in Patients With Virological Failure During Long-term Use of Darunavir in People With HIV. The ANRS CO3 Aquitaine Cohort.
Author	Chaussade H,Tumiotto C,Le Marec F,Leleux O,Lefèvre L,Lazaro E,Lafon ME,Nyamankolly E,Duffau P,Neau D,Bellecave P,Bonnet F
Evidence	All genotypes were reviewed according to the 2019 IAS and ANRSv29 mutation lists to determine PI drug resistance-associated mutations (RAMs): V11I, V32I, L33F, I47V, I50V, I54L/M, T74P, L76V, I84V, L89V.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation