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Mutation Information
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Mutation Site
|
I54L |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
Literature Information
|
PubMed PMID
|
27039930
|
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Published Year
|
2016 |
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Journal
|
Biochemistry |
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Title
|
Binding of Clinical Inhibitors to a Model Precursor of a Rationally Selected Multidrug Resistant HIV-1 Protease Is Significantly Weaker Than That to the Released Mature Enzyme. |
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Author
|
Park JH,Sayer JM,Aniana A,Yu X,Weber IT,Harrison RW,Louis JM |
|
Evidence
|
In contrast, mutations D30N, V32I, L33F, I47V, I54L, and I84V are present in PR20 but not in PRS17.
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HIV Mutation Detail Information