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Mutation Information
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Mutation Site
|
I54L |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
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Genotype/Subtype
|
A |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
25259833
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
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Journal
|
AIDS (London, England) |
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Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
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Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
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Evidence
|
Of the 243 patients who received one or more protease inhibitors, 32 (13%) had a study-defined protease inhibitor-resistance mutation most commonly L10F [4], K20T [3], V32I [2], L33F [7], M46I/L [9], I47V/A [2], I50L [4], F53L [4], I54V/L [3], Q58E [2], L76V [2], V82A/C [5], I84V [2], L89V [4], and L90M [3].
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HIV Mutation Detail Information