|
Mutation Information
|
Mutation Site
|
I54L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Genotype/Subtype
|
B;F1 |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
22877156
|
|
Clinical information
|
Yes
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2012 |
|
Journal
|
Virology journal |
|
Title
|
Clinical, epidemiological and molecular features of the HIV-1 subtype C and recombinant forms that are circulating in the city of São Paulo, Brazil. |
|
Author
|
Alcalde R,Guimarães ML,Duarte AJ,Casseb J |
|
Evidence
|
Secondary resistance mutations in the PR region were detected in individuals infected with subtypes B and F1 (G73S, I50L/V, I54L, I84V, L33F, L89V, V11I, V32I), and in the RT region (K101E, L100I, P225H, V108I, Y181C, Y188L). The mutations K65R, Q151M, Y115F were identified only in subtype B samples.
|
|
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HIV Mutation Detail Information