HIV Mutation Detail Information

> I50V Search Result

Mutation Information

Mutation Site	I50V
Mutation Type	Amino acid level
Gene/Protein/Region Type	PR
Relevant Drug	bictegravir (BIC);emtricitabine (FTC);tenofovir alafenamide
Country	Australia;Europe;North America

Literature Information

PubMed PMID	31430369
Disease	HIV infection/AIDS
Published Year	2019
Journal	The Journal of antimicrobial chemotherapy
Title	Switching to bictegravir/emtricitabine/tenofovir alafenamide maintained HIV-1 RNA suppression in participants with archived antiretroviral resistance including M184V/I.
Author	Andreatta K,Willkom M,Martin R,Chang S,Wei L,Liu H,Liu YP,Graham H,Quirk E,Martin H,White KL
Evidence	Primary PI-R substitutions observed were: M46I/L (n=22), L90M (n=13), D30N (n=9), V82A/L/T (n=7), I84V (n=5), I47V, N83D and N88S (n=2 each), and V32I, I50V, I54L, Q58E and L76V (n=1 each).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation