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Mutation Information
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Mutation Site
|
I47V |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
PR |
|
Viral Reference
|
K03455.1
|
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Relevant Drug
|
PIs |
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Country
|
China |
Literature Information
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PubMed PMID
|
29870534
|
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Disease
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HIV infection/AIDS
|
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Published Year
|
2018 |
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Journal
|
PloS one |
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Title
|
Epidemiological surveillance of HIV-1 transmitted drug resistance among newly diagnosed individuals in Shijiazhuang, northern China, 2014-2015. |
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Author
|
Wang X,Liu X,Li F,Zhou H,Li J,Wang Y,Liu L,Liu S,Feng Y,Wang N |
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Evidence
|
Among PI-related TDRs, M46I/L was predicted to low resistance to Nelfinavir (NFV, 2.2%) and I47V coferring resisitance for FPV/r(I),IDV/r(I),LPV/r(I), TPV/r(I) and SQV/r(I). (Fig 1B).
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HIV Mutation Detail Information