Mutation Information
Mutation Site
|
I45T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PreS2 |
Genotype/Subtype
|
C |
Viral Reference
|
AF286594.1
|
Country
|
Korea |
Literature Information
PubMed PMID
|
20119580
|
Clinical information
|
Yes
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
Published Year
|
2010 |
Journal
|
Journal of Korean medical science |
Title
|
Hepatitis B viral surface mutations in patients with adefovir resistant chronic hepatitis B with A181T/V polymerase mutations. |
Author
|
Kim JH,Jung YK,Joo MK,Kim JH,Yim HJ,Park JJ,Kim JS,Bak YT,Yeon JE,Byun KS |
Evidence
|
V32A, I45T, and T50I mutations were detected in the patients with HCC, both groups equally.
|
|
|