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Mutation Information
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Mutation Site
|
I34V |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Gag |
Literature Information
|
PubMed PMID
|
31622432
|
|
Published Year
|
2019 |
|
Journal
|
PloS one |
|
Title
|
Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study. |
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Author
|
Dicker I,Zhang S,Ray N,Beno BR,Regueiro-Ren A,Joshi S,Cockett M,Krystal M,Lataillade M |
|
Evidence
|
Finally, two additional substitutions emerged in the MA region: I34V appeared at passage 3 at 30% and gradually increased to 70%, until the selection was terminated on day 113, while V35I appeared transiently (~20%) between passages 7 and 9 and was then lost.
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HIV Mutation Detail Information