Mutation Information
Mutation Site
|
I333I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gag |
Literature Information
PubMed PMID
|
31622432
|
Published Year
|
2019 |
Journal
|
PloS one |
Title
|
Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study. |
Author
|
Dicker I,Zhang S,Ray N,Beno BR,Regueiro-Ren A,Joshi S,Cockett M,Krystal M,Lataillade M |
Evidence
|
In cultures of wild-type virus treated with GSK3532795, the emergence of I333V was observed, while in cultures of V370A-containing virus emergence of V362I occurred (in two cultures), with mixtures of H219H/Q and I333I/V in another set of V370A cultures.
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