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Mutation Information
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Mutation Site
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I31V |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
Vif |
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Viral Reference
|
K03455.1
|
Literature Information
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PubMed PMID
|
31665623
|
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Published Year
|
2019 |
|
Journal
|
Cell reports |
|
Title
|
HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators. |
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Author
|
Salamango DJ,Ikeda T,Moghadasi SA,Wang J,McCann JL,Serebrenik AA,Ebrahimi D,Jarvis MC,Brown WL,Harris RS |
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Evidence
|
Surprisingly, reversion of I31V alone nearly abolished EGFP-PPP2R5A degradation (with no effect on APOBEC3G-EGFP degradation), whereas no other single mutants had any effect.
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HIV Mutation Detail Information