Mutation Information
Mutation Site
|
I315R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Tax |
Combined Mutation
|
tax.P316S+tax.I315R |
Literature Information
PubMed PMID
|
8756622
|
Published Year
|
1996 |
Journal
|
Molecular and cellular biology |
Title
|
Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA. |
Author
|
Clemens KE,Piras G,Radonovich MF,Choi KS,Duvall JF,DeJong J,Roeder R,Brady JN |
Evidence
|
The M3 (F13A G14S), M16 (P92A P93S), M19(Q126A, H127S), and M45 (I315R, P316S) mutants were shown previously to transactivate, often weakly, both the HTLV-1 and HIV-1 LTR promoters
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