HBV Mutation Detail Information

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Mutation Information

Mutation Site	I27V
Mutation Type	Amino acid level
Gene/Protein/Region Type	C
Country	China

Literature Information

PubMed PMID	21181915
Disease	Chronic hepatitis B
Published Year	2011
Journal	Journal of medical virology
Title	Presence of valine at position 27 of the hepatitis B virus core gene is associated with severe liver inflammation in Chinese patients.
Author	Yang L,Ma S,Hu X,Xiao L,Wang Z,Li Y,Zhou B,Abbott WG,Hou J
Evidence	The frequency of the I27V mutation in the HBV core gene, which produces a core 18-27 peptide capable of binding HLA-A*02, was compared in Chinese patients with severe liver inflammation (n = 77, including 39 with acute-on-chronic liver failure), moderate liver inflammation (n = 44) and inactive disease (n = 45).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation