Mutation Information
Mutation Site
|
I27R |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E6 |
Amino acid_Mutation
|
T183G |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
AY686579
|
Country
|
Mexico |
Literature Information
PubMed PMID
|
28036379
|
Disease
|
Cervical carcinoma
|
Published Year
|
2016 |
Journal
|
PloS one |
Title
|
Different Association of Human Papillomavirus 16 Variants with Early and Late Presentation of Cervical Cancer. |
Author
|
Alfaro A,Juárez-Torres E,Medina-Martínez I,Mateos-Guerrero N,Bautista-Huerta M,Román-Bassaure E,Villegas-Sepúlveda N,Berumen J |
Evidence
|
The majority of the D2 isolates (92.0%, 46/50) had a T (reference position) to G substitution (Fig 1) in this position, resulting in an amino acid change of isoleucine to arginine in the protein (I27R).
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