HPV Mutation Detail Information

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Mutation Information
Mutation Site I27R
Mutation Type Amino acid level
Gene/Protein/Region Type E6
Amino acid_Mutation T183G
Genotype/Subtype HPV16
Viral Reference AY686579
Country Mexico
Literature Information
PubMed PMID 28036379
Disease Cervical carcinoma
Published Year 2016
Journal PloS one
Title Different Association of Human Papillomavirus 16 Variants with Early and Late Presentation of Cervical Cancer.
Author Alfaro A,Juárez-Torres E,Medina-Martínez I,Mateos-Guerrero N,Bautista-Huerta M,Román-Bassaure E,Villegas-Sepúlveda N,Berumen J
Evidence The majority of the D2 isolates (92.0%, 46/50) had a T (reference position) to G substitution (Fig 1) in this position, resulting in an amino acid change of isoleucine to arginine in the protein (I27R).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation