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Mutation Information
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Mutation Site
|
I25L |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Vpu |
Literature Information
|
PubMed PMID
|
32665270
|
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Published Year
|
2020 |
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Journal
|
mBio |
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Title
|
Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2. |
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Author
|
Hopfensperger K,Richard J,Stürzel CM,Bibollet-Ruche F,Apps R,Leoz M,Plantier JC,Hahn BH,Finzi A,Kirchhoff F,Sauter D |
|
Evidence
|
In agreement with previous findings, the exchange of 6 amino acids in the transmembrane domain (E15A, T16V, L17S, V19A, I25L, and V26L) was sufficient to confer efficient antitetherin activity to SIVcpz EK505 Vpu (Fig.
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HIV Mutation Detail Information