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Mutation Information
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Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
32790777
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
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Title
|
A recombinant human immunoglobulin with coherent avidity to hepatitis B virus surface antigens of various viral genotypes and clinical mutants. |
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Author
|
Jeong GU,Ahn BY,Jung J,Kim H,Kim TH,Kim W,Lee A,Lee K,Kim JH |
|
Evidence
|
Because the entire S gene is embedded within the viral polymerase gene, some viral polymerase mutations that confer drug resistance can cause amino acid sequence changes in HBsAg; major ones include E164D, W172L, L173F, I195M and W196L/S/V
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HBV Mutation Detail Information