|
Mutation Information
|
Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A;B;C;D |
|
Relevant Drug
|
lamivudine (LAM);telbivudine (LDT);adefovir dipivoxil (ADV);tenofovir (TNF);entecavir (ETV) |
|
Country
|
Canada;Italy;South Korea;China;Indonesia;United States;Turkey |
Literature Information
|
PubMed PMID
|
29713126
|
|
Published Year
|
2018 |
|
Journal
|
World journal of gastroenterology |
|
Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
|
Author
|
Choi YM,Lee SY,Kim BJ |
|
Evidence
|
The mutations rtA181T/V, rtM204I, and rtM204V also cause the simultaneous HBsAg mutations, sW172 stop, sW196S/L/Stop, and sI195M, respectively
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HBV Mutation Detail Information