HBV Mutation Detail Information

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Mutation Information

Mutation Site	I195M
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	C
Viral Reference	AF286594
Country	Korea

Literature Information

PubMed PMID	23710315
Clinical information	Yes
Disease	Chronic hepatitis B
Published Year	2013
Journal	Gut and liver
Title	Quasispecies and pre-existing drug-resistant mutations of hepatitis B virus in patients with chronic hepatitis B.
Author	Kim DY,Chang HY,Lim SM,Kim SU,Park JY,Kim JK,Lee KS,Han KH,Chon CY,Ahn SH
Evidence	All patients showed at least one kind of concomitant envelope gene change, which overlaps the polymerase gene. In patient 1, changes of the P gene, rtW153Q, rtI169L, rtV173L, rtA181V, and rtM204V, corresponded to change of the S gene, sG145R, sF161H, sE164D, and sI195M, respectively (Table 4).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation