Mutation Information
Mutation Site
|
I195M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Literature Information
PubMed PMID
|
22082274
|
Disease
|
HBV associated liver disease
|
Published Year
|
2011 |
Journal
|
Biochemistry. Biokhimiia |
Title
|
Antiviral resistance mutations potentiate HBV surface antigen-induced transcription of hfgl2 prothrombinase gene. |
Author
|
Li W,Han M,Li Y,Chen D,Luo X,Ning Q |
Evidence
|
To investigate whether the nucleotide (nucleoside)-induced resistant mutations of HBs potentiate transcription of hfgl2 prothrombinase gene, we generated two mutant HB expression constructs harboring rtM204V/sI195M or rtM204I/sW196L mutations.
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