|
Mutation Information
|
Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
21671883
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2011 |
|
Journal
|
Current HIV research |
|
Title
|
Detection of hepatitis B virus variants in HBV monoinfected and HBV/HIV coinfected Iranian patients under lamivudine treatment. |
|
Author
|
Aghasadeghi MR,Bahramali G,Sadat SM,Farahani A,Mohraz M,Davar Siadat S,Mostafavi E,Memarnejadian A,Ardestani MS,Vahabpour R,Saraji AA,Delbaz SA |
|
Evidence
|
The frequency of two major HBV surface mutations of sI195M (rtM204V) and sW196S/L/stop, which reduce the binding of anti-HBs antibody to HBsAg, was significantly higher in HBV monoinfected individuals than coinfected patients (P=0.01 and P
|
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HBV Mutation Detail Information