|
Mutation Information
|
Mutation Site
|
I195M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.V209A+s.I195M+s.S193L+s.V184E+s.S174T+s.E164D+s.S155P+s.S53L;s.I195M;s.V209L+s.S207N+s.I195M+s.L175F;s.L213I+s.V194A+s.I195M+s.S143T+s.Y134F+s.T131N+s.R122K+s.T68I;s.I195M+s.S171L+s.S171F+s.E164A;s.L213I+s.L209V+s.I195M+s.V194A+s.A168V+s.E164D+s.F161Y+s.G159A+s.S143T+s.Y134F+s.T131N;s.I195M+s.T189I+s.Y134N;s.Y206L+s.I195M;s.P211R+s.I195M;s.I195M+s.V180A+s.A168V+s.Y134H+s.T123N;s.V209L+s.S207N+s.I195M |
|
Genotype/Subtype
|
A;D |
|
Relevant Drug
|
lamivudine (LAM);tenofovir (TDF);adefovir dipivoxil (ADV);emtricitabine (FTC);entecavir (ETV) |
|
Country
|
Rome |
Literature Information
|
PubMed PMID
|
19442845
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Journal of virological methods |
|
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
|
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
|
Evidence
|
Table 1
|
|
|
HBV Mutation Detail Information