HBV Mutation Detail Information

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Mutation Information
Mutation Site I195M
Mutation Type Amino acid level
Gene/Protein/Region Type S
Country Spain
Literature Information
PubMed PMID 18167643
Disease HBV-HIV coinfection
Published Year 2007
Journal Journal of acquired immune deficiency syndromes (1999)
Title Selection of hepatitis B virus (HBV) vaccine escape mutants in HBV-infected and HBV/HIV-coinfected patients failing antiretroviral drugs with anti-HBV activity.
Author Sheldon J,Ramos B,Garcia-Samaniego J,Rios P,Bartholomeusz A,Romero M,Locarnini S,Zoulim F,Soriano V
Evidence In contrast, 3TC-resistance-associated mutations rtV173L, rtM204V/I, and rtV207I may simultaneously alter the S gene, causing critical antigenic changes in the C terminal region of HBsAg, as a result of producing mutations sE164D, sI195M, sW196S/L/stop, and sM198I or sW199stop, respectively.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation