HBV Mutation Detail Information

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Mutation Information
Mutation Site I195M
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype A
Country Argentina
Literature Information
PubMed PMID 17506609
Disease HBV-HIV coinfection
Published Year 2007
Journal AIDS research and human retroviruses
Title Hepatitis B virus genotype distribution and its lamivudine-resistant mutants in HIV-coinfected patients with chronic and occult hepatitis B.
Author Quarleri J,Moretti F,Bouzas MB,Laufer N,Carrillo MG,Giuliano SF,Pérez H,Cahn P,Salomon H
Evidence The triple mutant rtV173L plus rtL180M plus rtM204V seen in two individuals with genotype A HBV infection causes concomitant amino acid substitutions at positions 164 and 195 (sE164D plus sI195M) in the HBsAg protein as a result of the overlapping reading frames of the envelope and polymerase genes.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation