|
Mutation Information
|
Mutation Site
|
I152L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
LMP1 |
Literature Information
|
PubMed PMID
|
25436768
|
|
Published Year
|
2012 |
|
Journal
|
Pathogens (Basel, Switzerland) |
|
Title
|
Epstein-barr virus sequence variation-biology and disease. |
|
Author
|
Tzellos S,Farrell PJ |
|
Evidence
|
Similarly, investigation of variant LMP1 sequences in HIV patients in Switzerland identified polymorphisms (I124V/I152L and F144I/D150A/L151I), which were markers of increased NF-kappaB activation in vitro but were not associated with EBV-associated Hodgkin Lymphoma.
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EBV Mutation Detail Information