|
Mutation Information
|
Mutation Site
|
I126S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
X04615
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26613893
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2016 |
|
Journal
|
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases |
|
Title
|
Mutations in the S gene and in the overlapping reverse transcriptase region in chronic hepatitis B Chinese patients with coexistence of HBsAg and anti-HBs. |
|
Author
|
Ding F,Miao XL,Li YX,Dai JF,Yu HG |
|
Evidence
|
Mutation sI126S/T within the "a" determinant was the most frequent change, and only patients from group I had the sQ129R, sG130N, sF134I, sG145R amino acid changes, which are known to alter immunogenicity.
|
|
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HBV Mutation Detail Information