|
Mutation Information
|
Mutation Site
|
I126S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
22170538
|
|
Published Year
|
2012 |
|
Journal
|
Journal of medical virology |
|
Title
|
Comprehensive analysis of the prevalence of hepatitis B virus escape mutations in the major hydrophilic region of surface antigen. |
|
Author
|
Ma Q,Wang Y |
|
Evidence
|
Several important mutations (T/I126S, Q129H, G130N, S143L, D144A, G145A, and G145R) involved in diagnostic failure, combined with escape from vaccine or HBIG therapy (Table I) were found with a frequency of no less than 1%, and such mutations were prevalent in single or multiple genotypes.
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HBV Mutation Detail Information