Mutation Information
Mutation Site
|
I126S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
C |
Viral Reference
|
AF286594
|
Relevant Drug
|
lamivudine (LAM) |
Country
|
Korea |
Literature Information
PubMed PMID
|
15953865
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2005 |
Journal
|
Journal of Korean medical science |
Title
|
Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapy. |
Author
|
Lee SY,Choi MS,Lee D,Lee JH,Koh KC,Paik SW,Yoo BC |
Evidence
|
Sequencing of the 'a' determinant revealed amino acid substitutions as I126S, T131N, M133T, and S136Y.
|
|
|