Mutation Information
Mutation Site
|
I126N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
C |
Country
|
Vietnam |
Literature Information
PubMed PMID
|
28673869
|
Disease
|
HBV infection
|
Published Year
|
2017 |
Journal
|
Virus research |
Title
|
Impact of deletions and mutations in Hepatitis B virus envelope proteins on serological profile and clinical evolution. |
Author
|
Malve B,Eschlimann M,Galgey S,Fenaux H,Zoulim F,Goehringer F,Rabaud C,May T,Jeulin H,Schvoerer E |
Evidence
|
CD8(+)/CD4(+) T-cell epitopes and B-cell epitopes in the major hydrophilic region (MHR), such as sI126N and sG145R possibly involved in the rare coexisting Hepatitis B surface Antigen (HBsAg)/anti-HBs serological pattern.
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