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HIV Mutation Detail Information

> I109A Search Result


Mutation Information
Mutation Site I109A
Mutation Type Amino acid level
Gene/Protein/Region Type Nef
Literature Information
PubMed PMID 33109760
Published Year 2020
Journal mBio
Title HIV-1 Nef Interacts with LMP7 To Attenuate Immunoproteasome Formation and Major Histocompatibility Complex Class I Antigen Presentation.
Author Yang Y,Liu W,Hu D,Su R,Ji M,Huang Y,Shereen MA,Xu X,Luo Z,Zhang Q,Liu F,Wu K,Liu Y,Wu J
Evidence LMP7 interacted strongly with Nef(1 to 115), Nef(1 to 115)-(I109A), Nef(1 to 115)-(L110A), Nef(1 to 115)-(D111A), Nef(1 to 15)-(W113A), and Nef(1 to 115)-(I114A);weakly with Nef(1 to 115)-(L112A);and minimally with Nef(1 to 115)-(Y115A) (Fig. 3K).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation