HBV Mutation Detail Information

> I105V Search Result

Mutation Information

Mutation Site	I105V
Mutation Type	Amino acid level
Gene/Protein/Region Type	C
Genotype/Subtype	A
Viral Reference	X02763
Country	Asia‐Pacific;Europe

Literature Information

PubMed PMID	32579776
Disease	Chronic hepatitis B
Published Year	2020
Journal	Journal of viral hepatitis
Title	Virology analysis of chronic hepatitis B virus-infected patients treated for 28 days with JNJ-56136379 monotherapy.
Author	Verbinnen T,Hodari M,Talloen W,Berke JM,Blue D,Yogaratnam J,Vandenbossche J,Shukla U,De Meyer S,Lenz O
Evidence	One placebo‐treated patient (GT‐E, HBeAg‐negative) showed emerging I105T and I105V substitutions (FC = 2.7 and 1.4, respectively) at sequence‐read frequencies of 19% and 16% at day 29 (patient ID #10, Table 3).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation