|
Mutation Information
|
Mutation Site
|
H87R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
CA |
|
Relevant Drug
|
IFN-beta |
Literature Information
|
PubMed PMID
|
31941344
|
|
Published Year
|
2020 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
The 4th and 112th Residues of Viral Capsid Cooperatively Modulate Capsid-CPSF6 Interactions of HIV-1. |
|
Author
|
Saito A,Sultana T,Ode H,Nohata K,Samune Y,Nakayama EE,Iwatani Y,Shioda T |
|
Evidence
|
We recently identified a Q4R mutation in CA after propagation of an interferon (IFN)-beta-hypersensitive CA mutant, RGDA/Q112D (H87R, A88G, P90D, P93A and Q112D) virus, in IFN-beta-treated cells.
|
|
|
HIV Mutation Detail Information