|
Mutation Information
|
Mutation Site
|
H78Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Amino acid_Mutation
|
C335T |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
U89348
|
|
Country
|
India |
Literature Information
|
PubMed PMID
|
18199779
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2008 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India. |
|
Author
|
Pande S,Jain N,Prusty BK,Bhambhani S,Gupta S,Sharma R,Batra S,Das BC |
|
Evidence
|
Forty-two (70%) patients showed seven different types of E6 gene mutations, of which four, G145T, C335T, T350G, and T527A, were missense mutations: glutamine→histidine (Q14H), histidine→tyrosine (H78Y), leucine→valine (L83V), and serine→threonine (S142T), respectively.
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HPV Mutation Detail Information