HIV Mutation Detail Information

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Mutation Information
Mutation Site H71R
Mutation Type Amino acid level
Gene/Protein/Region Type Vpr
Literature Information
PubMed PMID 27343732
Published Year 2016
Journal Virology
Title HIV-1 Vpr increases Env expression by preventing Env from endoplasmic reticulum-associated protein degradation (ERAD).
Author Zhang X,Zhou T,Frabutt DA,Zheng YH
Evidence To understand how Vpr could increase Env expression, we introduced 6 mutations into these regions of Vpr, which include A30L, F34I, W54R, Q65R, and H71R.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation