HPV Mutation Detail Information

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Mutation Information

Mutation Site	H35Q
Mutation Type	Amino acid level
Gene/Protein/Region Type	E2
Amino acid_Mutation	C2860A
Genotype/Subtype	HPV16
Viral Reference	HQ644251.1
Country	China

Literature Information

PubMed PMID	30008422
Disease	Cervical carcinoma
Published Year	2018
Journal	Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Title	The association of human papillomavirus type 16 E2 variations with cervical cancer in a Han Chinese population.
Author	Dai S,Yao Y,Yan Z,Zhou Z,Shi L,Wang X,Sun L,Zhang R,Yao Y
Evidence	Among the sixteen variations, C2860A (H35Q), A3181C (E142D), G3182A (A143T), and T3224A (L157I) were located in the transactivation domain; A3362G (N203D), C3377G (P208A), T3387C (I211T), C3516A (T254N), T3517C (T254N), A3538C (S261S) and T3566G (F271V) were located in the hinge region; and T3664C (Y303Y), T3694A (T313T), T3706C (S317S), G3778T (W341C), and T3805G (V350V) were located in the DNA binding domain.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation