|
Mutation Information
|
Mutation Site
|
H330R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
|
Viral Reference
|
K03455.1
|
|
Immune Escape
|
Y |
Literature Information
|
PubMed PMID
|
30709739
|
|
Published Year
|
2019 |
|
Journal
|
Immunity |
|
Title
|
An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes. |
|
Author
|
Dingens AS,Arenz D,Weight H,Overbaugh J,Bloom JD |
|
Evidence
|
For example, while the overall effect of all mutations at site 330 was similar between 10-1074 and PGT121, H330R escapes 10-1074 but not PGT121 (Figure 3A,B, validated by TZM-bl neutralization assays in Figure S3).
|
|
|
HIV Mutation Detail Information