Mutation Information
Mutation Site
|
H2P |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
E7 |
Genotype/Subtype
|
HPV16 |
Literature Information
PubMed PMID
|
12239337
|
Published Year
|
2002 |
Journal
|
Journal of virology |
Title
|
Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells. |
Author
|
Helt AM,Funk JO,Galloway DA |
Evidence
|
In contrast, E7 CVQ68-70AAA and, unexpectedly, E7 H2P were not significantly better than vector at inducing S phase (Fig. (Fig.4D4D and Table Table2).2).
|
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