HIV Mutation Detail Information

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Mutation Information
Mutation Site H27A
Mutation Type Amino acid level
Gene/Protein/Region Type Vif
Literature Information
PubMed PMID 24422669
Published Year 2014
Journal Retrovirology
Title HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3.
Author Evans SL,Schön A,Gao Q,Han X,Zhou X,Freire E,Yu XF
Evidence Also as expected, Vif mutant, H108A was incapable of binding Cul5, however maintained its ability to bind both Elo B/C and CBF-β (Figure 4A, lane 4).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation