|
Mutation Information
|
Mutation Site
|
H228D |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
L1 |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
25793187
|
|
Disease
|
Low grade squamous intraepithelial lesion;
High grade squamous intraepithelial lesion
|
|
Published Year
|
2015 |
|
Journal
|
BioMed research international |
|
Title
|
Prevalence of human papillomavirus variants and genetic diversity in the L1 gene and long control region of HPV16, HPV31, and HPV58 found in North-East Brazil. |
|
Author
|
Gurgel AP,Chagas BS,do Amaral CM,Nascimento KC,Leal LR,Silva Neto Jda C,Cartaxo Muniz MT,de Freitas AC |
|
Evidence
|
The C6240G variation, which leads to H228D in the EF loop of the L1 protein, was observed in 100% of the samples and is embedded in B-cell and T-cell epitopes.
|
|
|
HPV Mutation Detail Information