HIV Mutation Detail Information

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Mutation Information
Mutation Site H221Y
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug NNRTIs;NRTIs
Country China
Literature Information
PubMed PMID 33252379
Disease HIV infection/AIDS
Published Year 2020
Journal Chinese medical journal
Title Efficacy and safety of the long-acting fusion inhibitor albuvirtide in antiretroviral-experienced adults with human immunodeficiency virus-1: interim analysis of the randomized, controlled, phase 3, non-inferiority TALENT study.
Author Su B,Yao C,Zhao QX,Cai WP,Wang M,Lu HZ,Chen YY,Liu L,Wang H,He Y,Zheng YH,Li LH,Chen JF,Yu JH,Zhu B,Zhao M,Sun YT,Lun WH,Xia W,Sun LJ,Dai LL,Jiang TY,Wang MX,Zheng QS,Peng HY,Wang Y,Lu RJ,Hu JH,Xing H,Shao YM,Xie D,Zhang T,Zhang FJ,Wu H,TALENT Study Team.
Evidence NNRTI resistance mutations (Y181C and H221Y) emerged in only one patient from the NRTI group.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation