Mutation Information
Mutation Site
|
H221Y |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NNRTIs;NRTIs |
Country
|
China |
Literature Information
PubMed PMID
|
33252379
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
Chinese medical journal |
Title
|
Efficacy and safety of the long-acting fusion inhibitor albuvirtide in antiretroviral-experienced adults with human immunodeficiency virus-1: interim analysis of the randomized, controlled, phase 3, non-inferiority TALENT study. |
Author
|
Su B,Yao C,Zhao QX,Cai WP,Wang M,Lu HZ,Chen YY,Liu L,Wang H,He Y,Zheng YH,Li LH,Chen JF,Yu JH,Zhu B,Zhao M,Sun YT,Lun WH,Xia W,Sun LJ,Dai LL,Jiang TY,Wang MX,Zheng QS,Peng HY,Wang Y,Lu RJ,Hu JH,Xing H,Shao YM,Xie D,Zhang T,Zhang FJ,Wu H,TALENT Study Team. |
Evidence
|
NNRTI resistance mutations (Y181C and H221Y) emerged in only one patient from the NRTI group.
|
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