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Mutation Information
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Mutation Site
|
H221Y |
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Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
entecavir (ETV);efavirenz (EFV);nevirapine (NPV);lamivudine (LAM);emtricitabine (FTC);zidovudine (AZT);didanosine (DDI);emtricitabine (FTC) |
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Country
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Togo |
Literature Information
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PubMed PMID
|
21663632
|
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Disease
|
HIV infection/AIDS
|
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Published Year
|
2011 |
|
Journal
|
Journal of the International AIDS Society |
|
Title
|
High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lomé, Togo. |
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Author
|
Dagnra AY,Vidal N,Mensah A,Patassi A,Aho K,Salou M,Monleau M,Prince-David M,Singo A,Pitche P,Delaporte E,Peeters M |
|
Evidence
|
Importantly, eight patients were already predicted to be resistant to etravirine, the new NNRTI, either because they harboured the single Y181V mutation (n = 3) or due to the presence of both Y181C and H221Y mutations (n = 5).
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HIV Mutation Detail Information