EBV Mutation Detail Information

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Mutation Information

Mutation Site	H213L
Mutation Type	Amino acid level
Gene/Protein/Region Type	BKRF3

Literature Information

PubMed PMID	24872582
Published Year	2014
Journal	Journal of virology
Title	Uracil DNA glycosylase BKRF3 contributes to Epstein-Barr virus DNA replication through physical interactions with proteins in viral DNA replication complex.
Author	Su MT,Liu IH,Wu CW,Chang SM,Tsai CH,Yang PW,Chuang YC,Lee CP,Chen MR
Evidence	In complementation assays, the catalytic mutant BKRF3(Q90L,D91N) restored viral DNA replication, whereas the leucine loop mutant BKRF3(H213L) only partially rescued viral DNA replication, coupled with a reduced ability to interact with the viral DNA polymerase and Rta.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation