|
Mutation Information
|
Mutation Site
|
H114Y |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Viral Reference
|
Q76353
|
|
Relevant Drug
|
raltegravir (RAL) |
Literature Information
|
PubMed PMID
|
31551948
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
Frontiers in microbiology |
|
Title
|
Raltegravir-Induced Adaptations of the HIV-1 Integrase: Analysis of Structure, Variability, and Mutation Co-occurrence. |
|
Author
|
Machado LA,Gomes MFDC,Guimarães ACR |
|
Evidence
|
In VG1 two resistance-related positions (114 and 121) had zero entropy in both datasets, probably because the resistance mutation H114Y is rare, and F121Y is rarely selected in vivo by RAL.
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HIV Mutation Detail Information