Mutation Information
Mutation Site
|
G89V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
CA |
Literature Information
PubMed PMID
|
33758083
|
Published Year
|
2021 |
Journal
|
mBio |
Title
|
Cytoplasmic CPSF6 Regulates HIV-1 Capsid Trafficking and Infection in a Cyclophilin A-Dependent Manner. |
Author
|
Zhong Z,Ning J,Boggs EA,Jang S,Wallace C,Telmer C,Bruchez MP,Ahn J,Engelman AN,Zhang P,Watkins SC,Ambrose Z |
Evidence
|
Because G89V HIV-1 is restricted by CPSF6-358 and thus can still bind CPSF6, we expected that this virus would induce CPSF6-GFP puncta that would not increase in number in the presence of CsA, which is what was observed (Fig.
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